Benzoyl peroxide is a common acne-fighting ingredient available by prescription and over the counter, which has the potential to break down into benzene. In March 2024, a petition was filed with the U.S. Food and Drug Administration (FDA). This petition expresses concerns that benzene, a cancer-causing substance, may be found in acne products containing benzoyl peroxide when these products are exposed to higher temperatures.
No petition has currently been raised in the UK or EU as of March 2024, but this position may change.
Most consumers do not store personal care products in the conditions in which Valisure tested the products. More information is needed to know if/how benzoyl peroxide may degrade into benzene at room temperature. Benzoyl peroxide has been a key acne-fighting ingredient used for many years. While there are no direct alternatives to benzoyl peroxide, your dermatologist can help you find other options if you are uncomfortable using benzoyl peroxide in your acne regimen as we learn more.
Other over the counter or prescription only treatment options include topical adapalene, salicylic acid, or azelaic acid.
What is benzene — and what makes it a human carcinogen?
Benzene is a colourless, highly flammable chemical that is used widely to make products, including drugs, detergents, dyes, plastics and lubricants. It is also found naturally in car fuel and cigarette smoke. Benzene can cause cells not to work correctly, and the seriousness depends on the amount, route, and length of time of exposure, as well as the age and pre-existing medical condition of the exposed person.
Benzoyl peroxide is a common active ingredient in acne-fighting personal care products and some prescription items. Benzene is not intended to be included in these products. In some personal care products contaminated with benzene, benzene is introduced during manufacturing. In the case of products with benzoyl peroxide as an active ingredient, the benzoyl peroxide can break down, which introduces benzene into the product.
What products were found to contain benzene?
Valisure’s research was performed on dozens of over-the counter benzoyl peroxide products. However, little information is provided about which products had benzene detected at baseline (and how much).
How can patients continue treating their acne while avoiding this contaminant?
There are many ingredients that help fight and prevent acne. If your current treatment plan includes benzoyl peroxide and you would like to avoid this ingredient, consult your Dermatologist or GP for alternate options.
How should I care for my skin if I have acne?
We recommend the following to care for your skin during acne treatment:
What else should I consider?
If you are concerned about ingredients in your acne skin care and medications, talk to a registered Consultant Dermatologist to develop an acne treatment plan that works for you.
Dr Tony Downs is a member of the British Association of Dermatologists, European Academy of Dermatology (EADV) and the American Academy of Dermatology and a consultant Dermatologist on the UK specialist register.
Dr Chris Bower is a member of the British Association of Dermatologists, the European Academy of Dermatology (EADV) and a consultant Dermatologist on the UK specialist register