Acne is chronic inflammatory disease that can cause severe psychological problems as well as being painful or itchy and for some people leave life-long acne scarring. Everyone gets some acne and for most the condition is short lived as a teenager. However, for others it can last for many years.
Treatments have not changed much over the years. Topicals for mild to moderate acne (such as salicylic acid, topical antibiotics, azelaic acid, benzyl peroxide and topical retinoids) or oral antibiotics when more severe. Oral contraception and oral spironolactone can be prescribed to women, but not men, because these tablets work by interfere and manipulating hormones.
Dermatologists prescribe isotretinoin usually when other treatments have failed but also for severe acne and where acne scarring is a concern.
Clascoterone cream has been available in the USA & Canada for over two years and has rapidly become a popular treatment. It is an androgen receptor inhibitor without any systemic absorption and so suitable for men and women. Clascoterone reduces oil (sebum) production and inflammation. It takes time to work – anywhere between 12 to 24 weeks. It is well tolerated and only causes mild skin irritation, redness and dryness.
Clascoterone cream can be used twice a day on its own or it can be combined with other topical or oral treatments, where these treatments have not been good enough to clear the acne completely in men or women. One tube of 60gm costs between £17 - £27 depending on the pharmacy. Please note this excludes consultation fees.
Women with Poly Cystic Ovarian Syndrome or hormonal acne would be ideally suited to this particular treatment.
Anecdotal published evidence also shows that it reduces skin oiliness.
If you are concerned about acne scarring or your acne treatment needs a refresh or if you are looking for a gentler treatment and less oily skin; then book a consultation, where we can take you through all available options.
Dr. Anthony Downs, Consultant Dermatologist delivered a very well attended virtual lecture on acne and acne scarring on Tuesday 27 July to GPs in the South West area.
NICE acne and acne scarring national guidelines were updated last month with additional attention and recommendations on the need to provide psychological support and acne scarring advice to patients with this medical disease.
Acne can have serious and persistent mental effects that can remain for many years and well after the acne has abated naturally or with treatment. Very few patients have access to laser treatment in the UK to treat acne scarring regardless of this recommendation in the NICE guidelines.
This evening these issues were debated as well mapping out current best clinical practice and what new emerging treatments may be available on prescription.